論文種別 原著論文
言語種別 英語
表題 Healthy lifestyle and preventable death: findings from the Japan Collaborative Cohort (JACC) Study
掲載誌名 正式名:Preventive medicine
略  称:Prev.Med.
ISSNコード:1096-0260/0091-7435
出版社 (United States)
巻・号・頁 48(5),pp.486-492
著者・共著者 Tamakoshi,A.;Tamakoshi,K.;Lin,Y.;Yagyu,K.;Kikuchi,S.;JACC Study Group
発行年月 2009/05
概要 キーワード:Adult;Aged;Cohort Studies;Cooperative Behavior;Female;Health Behavior;Humans;Japan/epidemiology;Life Style;Male;Middle Aged;Mortality/trends;Questionnaires;Risk Reduction Behavior
OBJECTIVE: To evaluate the effect of baseline combination of 6 lifestyle factors on all-cause mortality. METHODS: A total of 62,106 Japanese men and women aged 40-79 years were followed for 12.5 years on average. Hazard ratios and 95% confidence intervals (CIs) of all-cause mortality in relation to healthy lifestyle factors (not currently smoking, not heavily drinking, walking 1 h or more per day, sleeping 6.5 to 7.4 h per day, eating green-leafy vegetables almost daily and BMI between 18.5 and 24.9) were calculated from proportional-hazards regression models. We also estimated population-attributable fractions of death to address the impact of potential lifestyle modifications on mortality. RESULTS: Until 2003, 8497 deaths were observed. Age-adjusted HR of all-cause mortality for the group with 6 healthy lifestyle factors was 0.42 (95% CI: 0.32-0.56) among men and 0.49 (0.39-0.60) among women, respectively, compared with the group with 0-2 healthy lifestyle factors. Even at ages 60-79 years, a healthy lifestyle has a major impact on mortality. Had the subjects achieved even a 1-point increment in their lifestyle scores, death rates of 24.7% among men and 18.5% among women could have been reduced. CONCLUSION: We found an inverse association between baseline combination of 6 healthy lifestyle factors and all-cause mortality as well as its impact on preventable fraction of death. Our results also demonstrated that healthy lifestyle behaviors are important even in old age.
Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan. tamaa@aichi-med-u.ac.jp
PMID 19254743